Mr spectroscopy in the pediatric population is different from adults for two main reasons particularly in the newborn phase the brain undergoes biochemical maturation with dramatic changes of the normal biochemical fingerprint secondly brain diseases in the pediatric population are different from adult disorders. Mr spectroscopy of pediatric brain disorders is a groundbreaking survey of the many applications of mrs in pediatrics taking into account how dramatically the young brain matures as well as the unique presentation of many brain disorders in this population the first section of this book carefully explains the basic science and practice of mrs. Brain metabolic disorders are a major cause of mortality and morbidity in children proton mr spectroscopy is a sensitive diagnostic modality for these diseases the abnormalities in metabolite levels revealed by mr spectroscopy provide specific information in a wide range of metabolic disturbances continuing mr imaging and mr spectroscopy yields maximum diagnostic information in an mr . Proton magnetic resonance mr spectroscopy is a complementary method to mr imaging for understanding disease processes in the pediatric brain by demonstrating the presence of various metabolites in the sampled tissue mr spectroscopy helps in the understanding of abnormalities detected by mr imaging or clinical examination
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